Scientist-F & Head
Molecular Biology
DATE OF JOINING: 30th November, 2015
E-MAIL: pkm_8bh@yahoo.co.uk
• Ph.D. (Life Sciences), University of Rajasthan, Jaipur in collaboration with All India Institute of Medical Sciences (AIIMS), New Delhi
• M.Sc. (Life Sciences), University of Kalyani, Kalyani
1. Fellow of National Academy of Medical Sciences (FAMS), 2020
National Academy of Medical Sciences, New Delhi
2. Africa-India Mobility Fellow, 2020
DBT/Wellcome Trust India Alliance & African Academy of Sciences
3. Founder President Dr. T. C. Anandkumar Gold Medal Oration Award, 2017
Indian Society for Study of Reproduction & Fertility
4. Nominated as Foreign Affiliate Member, 2016
Foundation for Polish Science, Warsaw, Poland
5. Labhsetwar Foundation Award, 2015
Dr. Usha & Anant Labhsetwar Foundation, USA
6. Samanta Chandra Sekhar Award, 2013
Odisha Bigyan Academy, Department of Science & Technology, Govt. of Odisha
7. Fulbright Nehru Fellow, 2013
CIES-IIE, Washington DC, USA
8. Professor GP Talwar Gold Medal Award, 2012
Indian Society for Study of Reproduction & Fertility
9. Young Investigator Award, 2009
Department of Biotechnology, Ministry of Science & Technology, Govt. of India
10. JEM Young Scientist Award, 2008
Xth International Symposium on Dendritic Cells, October 1-5, 2008, Kobe, Japan
Israel, Italy, Japan, Russia and USA
Translational Research
Publications (List of 101 out of 156 published) :
1. Mishra PK*, Sharma J. Navigating the ethics of nanomedicine: are we lost in translation? Nanomedicine (Lond). 2021 Apr 26.
doi: 10.2217/nnm-2021-0054. PMID: 33900107. [IF = 4.30]
2. Shandilya R, Ranjan S, Khare S, Bhargava A, Goryacheva IY, Mishra PK*. Point-of-care diagnostics approaches for detection of lung cancer-associated circulating miRNAs. Drug Discov Today. 2021 Feb 26:S1359-6446(21)00108-2.
doi: 10.1016/j.drudis.2021.02.023. PMID: 33647439. [IF = 7.321]
3. Mishra PK*, Bunkar N, Singh RD, Kumar R, Gupta PK, Tiwari RR, Lodhi L, Bhargava A, Chaudhury K
Comparative profiling of epigenetic modifications among individuals living in different high and low air pollution zones: A pilot study from India. Environ Advances. 2021 July 21;4:100052.
doi.org/10.1016/j.envadv.2021.100052.
4. Bhardwaj A, Sapra L, Saini C, Azam Z, Mishra PK, Verma B, Mishra GC, Srivastava RK. COVID-19: Immunology, Immunopathogenesis and Potential Therapies. Int Rev Immunol. 2021 Feb 27:1-36.
doi: 10.1080/08830185.2021.1883600. PMID: 33641587. [IF = 4.58]
5. Sharma J, Parsai K, Raghuwanshi P, Ali SA, Tiwari V, Bhargava A, Mishra PK*. Emerging role of mitochondria in airborne particulate matter-induced immunotoxicity. Environ Pollut. 2021 Feb 1;270:116242.
doi: 10.1016/j.envpol.2020.116242. PMID: 33321436. [IF = 6.792]
6. Sapra L, Dar HY, Bhardwaj A, Pandey A, Kumari S, Azam Z, Upmanyu V, Anwar A, Shukla P, Mishra PK, Saini C, Verma B, Srivastava RK. Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice. Sci Rep. 2021 Jan 19;11(1):1807.
doi: 10.1038/s41598-020-80536-2. PMID: 33469043. [IF = 3.998]
7. Shandilya R, Bunkar N, Kumari R, Bhargava A, Chaudhury K, Goryacheva IY, Mishra PK*. Immuno-cytometric detection of circulating cell free methylated DNA, post-translationally modified histones and micro RNAs using semi-conducting nanocrystals. Talanta. 15 January 2021, 222:121516.
doi: 10.1016/j.talanta.2020.121516 [IF = 5.339]
8. Shandilya R, Pathak N, Lohiya NK, Sharma RS, Mishra PK*. Nanotechnology in reproductive medicine: Opportunities for clinical translation. Clin Exp Reprod Med. 2020 Dec;47(4):245-262.
doi: 10.5653/cerm.2020.03650. PMID: 33227186.
9. Mahor D, Kumari V, Vashisht K, Galgalekar R, Samarth RM, Mishra PK, Banerjee N, Dixit R, Saluja R, De S, Pandey KC. Elevated serum matrix metalloprotease (MMP-2) as a candidate biomarker for stable COPD. BMC Pulm Med. 2020 Nov 16;20(1):302.
doi: 10.1186/s12890-020-01323-3. PMID: 33198714. [IF = 2.813]
10. Sharma J, Chouksey A, Kumari R, Gupta PK, Tiwari R, Lodhi L, Srivastava RK, Bhargava A, Mishra PK*. Clostridium perfringens phospholipase C impairs innate immune response by inducing integrated stress response and mitochondrial-induced epigenetic modifications. Cell Signal. 2020 Sep 8;75:109776.
doi: 10.1016/j.cellsig.2020.109776. PMID: 32916276. [IF = 3.968]
11. Sharma J, Kumari R, Bhargava A, Tiwari R, Mishra PK*. Mitochondrial-induced Epigenetic Modifications: From Biology to Clinical Translation. Curr Pharm Des. 2021;27(2):159-176.
doi: 10.2174/1381612826666200826165735. PMID: 32851956. [IF = 2.575]
12. Bhargava A, Kumari R, Khare S, Gupta PK, Tiwari R, Rahman A, Chaudhury K, Goryacheva IY, Mishra PK*. Mapping the Mitochondrial Regulation of Epigenetic Modifications in Association with Carcinogenic and Noncarcinogenic Polycyclic Aromatic Hydrocarbon Exposure. Int J Toxicol. 2020 Sep/Oct;39(5):465-476.
doi: 10.1177/1091581820932875. PMID: 32588678. [IF = 1.255]
13. Mishra PK*, Shandilya R. Nanophotonic biosensors as point-of-care tools for preventive health interventions. Nanomedicine (Lond). 2020;15(16):1541-1544.
doi:10.2217/nnm-2020-0162. PMID: 32564708. [IF = 4.3]
14. Bhargava A, Mishra DK, Tiwari R, Lohiya NK, Goryacheva IY, Mishra PK*. Immune cell engineering: opportunities in lung cancer therapeutics. Drug Deliv Transl Res. 2020 Oct;10(5):1203-1227.
doi: 10.1007/s13346-020-00719-2. PMID: 32172351 [IF = 2.664]
15. Shandilya R, Sobolev AM, Bunkar N, Bhargava A, Goryacheva IY, Mishra PK*. Quantum dot nanoconjugates for immuno-detection of circulating cell-free miRNAs. Talanta. 2020 Feb 1;208:120486.
doi: 10.1016/j.talanta.2019.120486. PMID: 31816728. [IF = 5.339]
16. Bhargava A, Shukla A, Bunkar N, Shandilya R, Lodhi L, Kumari R, Gupta PK, Rahman A, Chaudhury K, Tiwari R, Goryacheva IY, Mishra PK*. Exposure to ultrafine particulate matter induces NF-κβ mediated epigenetic modifications. Environ Pollut. 2019 Sep;252(Pt A):39-50.
doi: 10.1016/j.envpol.2019.05.065. PMID: 31146237. [IF = 6.792]
17. Goryacheva OA, Vostrikova AM, Kokorina AA, Mordovina EA, Tsyupka DV, Bakal AA, Markin AV, Shandilya R, Mishra PK, Beloglazova NV, Goryacheva IY. Luminescent carbon nanostructures for microRNA detection. TrAC Trends in Analytical Chemistry. 2019 October 2019, 115613.
doi: 10.1016/j.trac.2019.07.024. [IF = 9.801]
18. Gupta P, Bhargava A, Kumari R, Lodhi L, Tiwari R, Gupta PK, Bunkar N, Samarth R, Mishra PK*. Impairment of Mitochondrial-Nuclear Cross Talk in Lymphocytes Exposed to Landfill Leachate. Environ Health Insights. 2019 Apr 2;13:1178630219839013.
doi: 10.1177/1178630219839013. PMID: 31168291.
19. Bunkar N, Shandilya R, Bhargava A, Samarth RM, Tiwari R, Mishra DK, Srivastava RK, Sharma RS, Lohiya NK, Mishra PK*. Nano-engineered flavonoids for cancer protection. Front Biosci (Landmark Ed). 2019 Mar 1;24:1097-1157.
doi: 10.2741/4771. PMID: 30844733. [IF = 2.747]
20. Goryacheva OA, Novikova AS, Drozd DD, Pidenko PS, Ponomaryeva TS, Bakal AA, Mishra PK, Beloglazova NV, Goryacheva IY. Water-dispersed luminescent quantum dots for miRNA detection. TrAC Trends in Analytical Chemistry. 2019 February; 111: 97-205.
doi: 10.1016/j.trac.2018.12.022. [IF = 9.801]
21. Shandilya R, Bhargava A, Bunkar N, Tiwari R, Goryacheva IY, Mishra PK*. Nanobiosensors: Point-of-care approaches for cancer diagnostics. Biosens Bioelectron. 2019 Apr 1;130:147-165.
doi: 10.1016/j.bios.2019.01.034. PMID: 30735948. [IF = 10.257]
22. Bhargava A, Srivastava RK, Mishra DK, Tiwari RR, Sharma RS, Mishra PK*. Dendritic cell engineering for selective targeting of female reproductive tract cancers. Indian J Med Res. 2018 Dec;148(Suppl):S50-S63.
doi: 10.4103/ijmr.IJMR_224_18. PMID: 30964081. [IF = 1.503]
23. Singh RD, Shandilya R, Bhargava A, Kumar R, Tiwari R, Chaudhury K, Srivastava RK, Goryacheva IY, Mishra PK*. Quantum Dot Based Nano-Biosensors for Detection of Circulating Cell Free miRNAs in Lung Carcinogenesis: From Biology to Clinical Translation. Front Genet. 2018 Dec 6;9:616.
doi: 10.3389/fgene.2018.00616. PMID: 30574163. [IF = 3.258]
24. Shukla A, Bunkar N, Kumar R, Bhargava A, Tiwari R, Chaudhury K, Goryacheva IY, Mishra PK*. Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms. Sci Total Environ. 2019 Mar 15;656:760-777. doi: 10.1016/j.scitotenv.2018.11.381. PMID: 30530146. [IF = 6.551]
25. Dar HY, Lone Y, Koiri RK, Mishra PK, Srivastava RK. Microcystin-leucine arginine (MC-LR) induces bone loss and impairs bone micro-architecture by modulating host immunity in mice: Implications for bone health. Environ Pollut. 2018 Jul;238:792-802.
doi: 10.1016/j.envpol.2018.03.059. PMID: 29626823. [IF = 6.792]
26. Mishra DK, Shandilya R, Mishra PK. Lipid based nanocarriers: a translational perspective. Nanomedicine - Nanotechnology Biology and Medicine. 2018 Jun 23;14(7):2023-2050.
doi:10.1016/j.nano.2018.05.021. PMID: 29944981. [IF = 5.182]
27. Srivastava RK, Dar HY, Mishra PK. Immunoporosis: Immunology of Osteoporosis-Role of T Cells. Front Immunol. 2018 Apr 5;9:657.
doi:10.3389/fimmu.2018.00657. PMID: 29675022. [IF = 5.085]
28. Dar HY, Pal S, Shukla P, Mishra PK, Tomar GB, Chattopadhyay N, Srivastava RK. Bacillus clausii inhibits bone loss by skewing Treg-Th17 cell equilibrium in postmenopausal osteoporotic mice model. Nutrition. 2018 Mar 20;54:118-128.
doi:10.1016/j.nut.2018.02.013. PMID: 29793054. [IF = 3.359]
29. Bhargava A, Tamrakar S, Aglawe A, Lad H, Srivastava RK, Mishra DK, Tiwari R, Chaudhury K, Goryacheva IY, Mishra PK*. Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes. Environ Pollut. 2018 Mar;234:406-419.
doi: 10.1016/j.envpol.2017.11.093. PMID: 29202419. [IF = 6.792]
30. Vandana, Singh AP, Singh J, Sharma R, Akhter M, Mishra PK, Saxena AK, Dixit R, Rathi B, Katyal A, Pandey KC. Biochemical characterization of unusual cysteine protease of P. falciparum, metacaspase-2 (MCA-2). Mol Biochem Parasitol. 2018 Mar;220:28-41. doi: 10.1016/j.molbiopara.2018.01.001. PMID: 29317266. [IF = 1.571]
31. Goryacheva OA, Mishra PK, Goryacheva IY. Luminescent quantum dots for miRNA detection. Talanta. 2018 Mar 1;179:456-465.
doi: 10.1016/j.talanta.2017.11.011. PMID: 29310260. [IF = 5.339]
32. Dar HY, Singh A, Shukla P, Anupam R, Mondal RK, Mishra PK, Srivastava RK. High dietary salt intake correlates with modulated Th17-Treg cell balance resulting in enhanced bone loss and impaired bone-microarchitecture in male mice. Sci Rep. 2018 Feb 6;8(1):2503.
doi: 10.1038/s41598-018-20896-y. PMID: 29410520. [IF = 3.998]
33. Dar HY, Shukla P, Mishra PK, Anupam R, Mondal RK, Tomar GB, Sharma V, Srivastava RK. Lactobacillus acidophilus inhibits bone loss and increases bone heterogeneity in osteoporotic mice via modulating Treg-Th17 cell balance. Bone Rep. 2018 Feb 5;8:46-56.
doi: 10.1016/j.bonr.2018.02.001. PMID: 29955622. [IF = 2.080]
34. Bhargava A, Bunkar N, Aglawe A, Pandey KC, Tiwari R, Chaudhury K, Goryacheva IY, Mishra PK*. Epigenetic Biomarkers for Risk Assessment of Particulate Matter Associated Lung Cancer. Curr Drug Targets. 2018;19(10):1127-1147.
doi:10.2174/1389450118666170911114342. PMID: 28891455. [IF = 1.582]
35. Bunkar N, Bhargava A, Chaudhury K, Sharma RS, Lohiya NK, Mishra PK*. Fetal nucleic acids in maternal plasma: from biology to clinical translation. Front Biosci (Landmark Ed). 2018 Jan 1;23:397-431. doi:10.2741/4597. PMID: 28930553. [IF = 2.747]
36. Bhargava A, Pathak N, Seshadri S, Bunkar N, Jain SK, Kumar DM, Lohiya NK, Mishra PK*. Pre-Clinical Validation of Mito-Targeted Nano-Engineered Flavonoids Isolated From Selaginella bryopteris (Sanjeevani) As A Novel Cancer Prevention Strategy. Anticancer Agents Med Chem. 2018;18(13):1860-1874.
doi:10.2174/1871520618666171229223919. PMID: 29298656. [IF = 2. 049]
37. Pandey KC, De S, Mishra PK. Role of Proteases in Chronic Obstructive Pulmonary Disease. Front Pharmacol. 2017 Aug 8;8:512.
doi:10.3389/fphar.2017.00512. PMID: 28848433. [IF = 4. 225]
38. Bhargava A, Pathak N, Sharma RS, Lohiya NK, Mishra PK*. Environmental Impact on Reproductive Health: Can Biomarkers Offer Any Help? J Reprod Infertil. 2017 Jul-Sep;18(3):336-340.
PMCID: PMC5641444. PMID: 29062799.
39. Mittra I, Samant U, Sharma S, Raghuram GV, Saha T, Tidke P, Pancholi N, Gupta D, Prasannan P, Gaikwad A, Gardi N, Chaubal R, Upadhyay P, Pal K, Rane B, Shaikh A, Salunkhe S, Dutt S, Mishra PK, Khare NK, Nair NK, Dutt A. Cell-free chromatin from dying cancer cells integrate into genomes of bystander healthy cells to induce DNA damage and inflammation. Cell Death Discov. 2017 May 29;3:17015.
doi:10.1038/cddiscovery.2017.15. PMID: 28580170 [IF = 4. 114]
40. Mishra DK, Balekar N, Mishra PK. Nanoengineered strategies for siRNA delivery: from target assessment to cancer therapeutic efficacy. Drug Deliv Transl Res. 2017 Apr;7(2):346-358.
doi: 10.1007/s13346-016-0352-5. PMID: 28050890. [IF = 2.664]
41. Bhargava A, Khare NK, Bunkar N, Chaudhury K, Pandey KC, Jain SK, Mishra PK*. Cell-Free Circulating Epigenomic Signatures: Non-Invasive Biomarker for Cardiovascular and Other Age-Related Chronic Diseases. Curr Pharm Des. 2017;23(8):1175-1187.
doi: 10.2174/1381612822666161027145359. PMID: 27817745. [IF = 2.208]
42. Bhargava A, Mishra DK, Jain SK, Srivastava RK, Lohiya NK, Mishra PK*. Comparative assessment of lipid based nano-carrier systems for dendritic cell based targeting of tumor re-initiating cells in gynecological cancers. Mol Immunol. 2016 Nov;79:98-112. doi: 10.1016/j.molimm.2016.10.003. PMID: 27764711. [IF = 3.641]
43. Bunkar N, Pathak N, Lohiya NK, Mishra PK*. Epigenetics: A key paradigm in reproductive health. Clin Exp Reprod Med. 2016 Jun;43(2):59-81.
doi: 10.5653/cerm.2016.43.2.59. PMID: 27358824.
44. Bhargava A, Khare NK, Bunkar N, Lenka RK, Mishra PK*. Role of mitochondrial oxidative stress on lymphocyte homeostasis in patients diagnosed with extra-pulmonary tuberculosis. Cell Biol Int. 2016 Feb;40(2):166-76.
doi:10.1002/cbin.10549. PMID: 26431927. [IF = 2.571]
45. Bunkar N, Bhargava A, Khare NK, Mishra PK*. Mitochondrial anomalies: driver to age associated degenerative human ailments. Front Biosci (Landmark). 2016 Jan 1;21:769-93.
doi:10.2741/4420. PMID: 26709805. [IF = 2.747]
46. Mishra DK, Dhote V, Bhargava A, Jain DK, Mishra PK. Amorphous solid dispersion technique for improved drug delivery: basics to clinical applications. Drug Deliv Transl Res. 2015 Dec;5(6):552-65.
doi: 10.1007/s13346-015-0256-9. PMID: 26306524. [IF = 2.664]
47. Mishra PK*, Bunkar N, Raghuram GV, Khare NK, Pathak N, Bhargava A. Epigenetic dimension of oxygen radical injury in spermatogonial epithelial cells. Reprod Toxicol. 2015 Apr;52:40-56.
doi: 10.1016/j.reprotox.2015.02.006. PMID: 25687723. [IF = 3.121]
48. Mittra I, Khare NK, Raghuram GV, Chaubal R, Khambatti F, Gupta D, Gaikwad A, Prasannan P, Singh A, Iyer A, Singh A, Upadhyay P, Nair NK, Mishra PK, Dutt A. Circulating nucleic acids damage DNA of healthy cells by integrating into their genomes. J Biosci. 2015 Mar;40(1):91-111.
doi: 10.1007/s12038-015-9508-6. PMID: 25740145. [IF = 1.645]
49. Mishra PK*, Raghuram GV, Bunkar N, Bhargava A, Khare NK. Molecular bio-dosimetry for carcinogenic risk assessment in survivors of Bhopal gas tragedy. Int J Occup Med Environ Health. 2015;28(6):921-39.
doi:10.13075/ijomeh.1896.00313. PMID: 26294196. [IF = 1.271]
50. Raghuram GV, Mishra PK*. Stress induced premature senescence: a new culprit in ovarian tumorigenesis? Indian J Med Res. 2014 Nov;140 Suppl:S120-9.
PMCID: PMC4345742. PMID: 25673532. [IF = 1.503]
51. Bhargava A, Bunkar N, Khare NK, Mishra D, Mishra PK*. Nanoengineered strategies to optimize dendritic cells for gastrointestinal tumor immunotherapy: from biology to translational medicine. Nanomedicine (Lond). 2014 Jul;9(14):2187-202.
doi: 10.2217/nnm.14.115. PMID: 25405796. [IF = 4.3]
52. Panwar H, Raghuram GV, Jain D, Ahirwar AK, Khan S, Jain SK, Pathak N, Banerjee S, Maudar KK, Mishra PK*. Cell cycle deregulation by methyl isocyanate: Implications in liver carcinogenesis. Environ Toxicol. 2014 Mar;29(3):284-97.
doi: 10.1002/tox.21757. PMID: 22223508. [IF = 3.118]
53. Mishra PK*, Raghuram GV, Jain D, Jain SK, Khare NK, Pathak N. Mitochondrial oxidative stress-induced epigenetic modifications in pancreatic epithelial cells. Int J Toxicol. 2014 Mar-Apr;33(2):116-29.
doi: 10.1177/1091581814524064. PMID: 24563415. [IF = 1.255]
54. Bhatnagar P, Dhote V, Mahajan SC, Mishra PK, Mishra DK. Solid dispersion in pharmaceutical drug development: from basics to clinical applications. Curr Drug Deliv. 2014;11(2):155-71. Review.
doi: 10.2174/15672018113109990044. PMID: 23859356. [IF = 1.582]
55. Khan S, Raghuram GV, Pathak N, Jain SK, Chandra DH, Mishra PK*. Impairment of mitochondrial-nuclear cross talk in neutrophils of patients with type 2 diabetes mellitus. Indian J Clin Biochem. 2014 Jan;29(1):38-44.
doi: 10.1007/s12291-013-0321-4. PMID: 24478547.
56. Bhargava A, Pathak N, Varshney S, Shrivastava M, Mishra PK*. Molecular detection of window phase hepatitis C virus infection in voluntary blood donors and health care workers in a cohort from central India. Indian J Community Med. 2014 Jan;39(1):51-2. doi: 10.4103/0970-0218.126362. PMID: 24696542.
57. Pathak N, Khan S, Bhargava A, Raghuram GV, Jain D, Panwar H, Samarth RM, Jain SK, Maudar KK, Mishra DK, Mishra PK*. Cancer chemopreventive effects of the flavonoid-rich fraction isolated from papaya seeds. Nutr Cancer. 2014;66(5):857-71.
doi: 10.1080/01635581.2014.904912. PMID: 24820939. [IF = 2.363]
58. Joshi R, Mishra PK, Joshi D, Santhosh SR, Parida MM, Desikan P, Gangane N, Kalantri SP, Reingold A, Colford JM Jr. Clinical presentation, etiology, and survival in adult acute encephalitis syndrome in rural Central India. Clin Neurol Neurosurg. 2013 Sep;115(9):1753-61.
doi: 10.1016/j.clineuro.2013.04.008. PMID: 23643180. [IF = 1.53]
59. Bhargava A, Mishra D, Khan S, Varshney SK, Banerjee S, Mishra PK*. Assessment of tumor antigen-loaded solid lipid nanoparticles as an efficient delivery system for dendritic cell engineering. Nanomedicine (Lond). 2013 Jul;8(7):1067-84.
doi: 10.2217/nnm.12.164. PMID: 23311961. [IF = 4.3]
60. Desikan P, De S, Pai NP, Mishra PK, Kumar K, Panwalkar N, Verma M, Hasan ZU, Maudar KK. An HIV1/2 point of care test on sputum for screening TB/HIV co-infection in Central India - Will it work? Asian Pac J Trop Med. 2013 Mar;6(3):216-9.
doi: 10.1016/S1995-7645(13)60026-7. PMID: 23375036. [IF = 1.94]
61. Mishra DK, Dhote V, Mishra PK. Transdermal immunization: biological framework and translational perspectives. Expert Opin Drug Deliv. 2013 Feb;10(2):183-200.
doi: 10.1517/17425247.2013.746660. PMID: 23256860. [IF = 4.887]
62. Bhargava A, Mishra D, Banerjee S, Mishra PK*. Engineered dendritic cells for gastrointestinal tumor immunotherapy: opportunities in translational research. J Drug Target. 2013 Feb;21(2):126-36.
doi: 10.3109/1061186X.2012.731069. PMID: 23061479. [IF = 3.38]
63. Panwar H, Jain D, Khan S, Pathak N, Raghuram GV, Bhargava A, Banerjee S, Mishra PK*. Imbalance of mitochondrial-nuclear cross talk in isocyanate mediated pulmonary endothelial cell dysfunction. Redox Biol. 2013 Jan 21;1:163-71.
doi:10.1016/j.redox.2013.01.009. PMID: 24024149. [IF = 9.986]
64. Mishra DK, Dhote V, Bhatnagar P, Mishra PK*. Engineering solid lipid nanoparticles for improved drug delivery: promises and challenges of translational research. Drug Deliv Transl Res. 2012 Aug;2(4):238-53.
doi:10.1007/s13346-012-0088-9. PMID: 25787030. [IF = 2.664]
65. Bhargava A, Mishra D, Banerjee S, Mishra PK*. Dendritic cell engineering for tumor immunotherapy: from biology to clinical translation. Immunotherapy. 2012 Jul;4(7):703-18.
doi: 10.2217/imt.12.40. PMID: 22853757. [IF = 2.964]
66. Mittra I, Nair NK, Mishra PK. Nucleic acids in circulation: are they harmful to the host? J Biosci. 2012 Jun;37(2):301-12.
doi: 10.1007/s12038-012-9192-8. PMID: 22581336. [IF = 1.645]
67. Mishra PK*. A pragmatic & translational approach of human biomonitoring to methyl isocyanate exposure in Bhopal. Indian J Med Res. 2012 Apr;135(4):479-84.
PMCID: PMC3385230. PMID: 22664494. [IF = 1.503]
68. Maudar KK, Gandhi P, Mishra PK, Varshney S, Punde R, Bhargav A. Novel approach for quantification of hepatitis C virus in liver cirrhosis using real-time reverse transcriptase PCR. J Gastrointest Surg. 2012 Jan;16(1):142-6;
doi: 10.1007/s11605-011-1750-0. PMID: 22048842. [IF = 2.573]
69. Dhote V, Bhatnagar P, Mishra PK, Mahajan SC, Mishra DK. Iontophoresis: a potential emergence of a transdermal drug delivery system. Sci Pharm. 2012 Jan-Mar;80(1):1-28.
doi: 10.3797/scipharm.1108-20. PMID: 22396901.
70. Khan S, Raghuram GV, Bhargava A, Pathak N, Chandra DH, Jain SK, Mishra PK*. Role and clinical significance of lymphocyte mitochondrial dysfunction in type 2 diabetes mellitus. Transl Res. 2011 Dec;158(6):344-59.
doi: 10.1016/j.trsl.2011.08.007. PMID: 22061042. [IF = 5.411]
71. Bhargava A, Raghuram GV, Pathak N, Varshney S, Jatawa SK, Jain D, Mishra PK*. Occult hepatitis C virus elicits mitochondrial oxidative stress in lymphocytes and triggers PI3-kinase-mediated DNA damage response. Free Radic Biol Med. 2011 Nov 1;51(9):1806-14.
doi: 10.1016/j.freeradbiomed.2011.08.009. PMID: 21893189. [IF = 6.17]
72. Mishra PK*, Raghuram GV, Bhargava A, Ahirwar A, Samarth R, Upadhyaya R, Jain SK, Pathak N. In vitro and in vivo evaluation of the anticarcinogenic and cancer chemopreventive potential of a flavonoid-rich fraction from a traditional Indian herb Selaginella bryopteris. Br J Nutr. 2011 Oct;106(8):1154-68.
doi: 10.1017/S0007114511001498. PMID: 21736819. [IF = 3.334]
73. Dubey V, Nahar M, Mishra D, Mishra PK, Jain NK. Surface structured liposomes for site specific delivery of an antiviral agent-indinavir. J Drug Target. 2011 May;19(4):258-69.
doi: 10.3109/1061186X.2010.499460. PMID: 20604740. [IF = 3.38]
74. Khan S, Bhargava A, Pathak N, Maudar KK, Varshney S, Mishra PK*. Circulating Biomarkers and their Possible Role in Pathogenesis of Chronic Hepatitis B and C Viral Infections. Indian J Clin Biochem. 2011 Apr;26(2):161-8.
doi: 10.1007/s12291-010-0098-7. PMID: 22468043.
75. Bhargava A, Punde R, Varshney S, Pathak N, Mishra PK*. A novel FRET probe-based approach for identification, quantification, and characterization of occult HCV infections in patients with cryptogenic liver cirrhosis. Indian J Pathol Microbiol. 2011 Apr-Jun;54(2):420-1.
doi: 10.4103/0377-4929.81609. PMID: 21623119.
76. Punde RP, Bhargava A, Varshney S, Pathak N, Shrivastava M, Mishra PK*. Ascertaining the prevalence of occult hepatitis B virus infection in voluntary blood donors: a study from Central India. Indian J Pathol Microbiol. 2011 Apr-Jun;54(2):408.
doi: 10.4103/0377-4929.81592. PMID: 21623110.
77. Mishra PK*, Raghuram GV, Bhargava A, Pathak N. Translation research in molecular disease diagnosis: bridging gap from laboratory to practice. J Glob Infect Dis. 2011 Apr;3(2):205-6.
doi: 10.4103/0974-777X.81705. PMID: 21731314.
78. Mishra PK*, Bhargava A, Pathak N, Desikan P, Maudar KK, Varshney S, Shrivastava R, Jain A. Molecular surveillance of hepatitis and tuberculosis infections in a cohort exposed to methyl isocyanate. Int J Occup Med Environ Health. 2011 Mar;24(1):94-101. doi: 10.2478/s13382-011-0006-2. PMID: 21468906. [IF = 1.271]
79. Jain D, Pathak N, Khan S, Raghuram GV, Bhargava A, Samarth R, Mishra PK*. Evaluation of cytotoxicity and anticarcinogenic potential of Mentha leaf extracts. Int J Toxicol. 2011 Mar;30(2):225-36.
doi: 10.1177/1091581810390527. PMID: 21300767. [IF = 1.255]
80. Mishra PK*, Raghuram GV, Jatawa SK, Bhargava A, Varshney S. Frequency of genetic alterations observed in cell cycle regulatory proteins and microsatellite instability in gallbladder adenocarcinoma: a translational perspective. Asian Pac J Cancer Prev. 2011;12(2):573-4.
PMID: 21545232.
81. Raghuram GV, Pathak N, Jain D, Panwar H, Pandey H, Jain SK, Mishra PK*. Molecular mechanisms of isocyanate induced oncogenic transformation in ovarian epithelial cells. Reprod Toxicol. 2010 Nov;30(3):377-86.
doi: 10.1016/j.reprotox.2010.05.087. PMID: 20685613. [IF = 3.121]
82. Mishra PK*, Bhargava A, Khan S, Pathak N, Punde RP, Varshney S. Prevalence of hepatitis C virus genotypes and impact of T helper cytokines in achieving sustained virological response during combination therapy: a study from Central India. Indian J Med Microbiol. 2010 Oct-Dec;28(4):358-62.
doi: 10.4103/0255-0857.71813. PMID: 20966569. [IF = 0.9]
83. Bhargava A, Khan S, Panwar H, Pathak N, Punde RP, Varshney S, Mishra PK*. Occult hepatitis B virus infection with low viremia induces DNA damage, apoptosis and oxidative stress in peripheral blood lymphocytes. Virus Res. 2010 Oct;153(1):143-50.
doi: 10.1016/j.virusres.2010.07.023. PMID: 20667493. [IF = 2.934]
84. Mishra PK*, Khan S, Bhargava A, Panwar H, Banerjee S, Jain SK, Maudar KK. Regulation of isocyanate-induced apoptosis, oxidative stress, and inflammation in cultured human neutrophils: isocyanate-induced neutrophils apoptosis. Cell Biol Toxicol. 2010 Jun;26(3):279-91.
doi: 10.1007/s10565-009-9127-9. PMID: 19455394. [IF = 6.284]
85. Mishra PK*, Gorantla VR, Bhargava A, Varshney S, Vashistha P, Maudar KK. Molecular detection of Mycobacterium tuberculosis in formalin-fixed, paraffin-embedded tissues and biopsies of gastrointestinal specimens using real-time polymerase chain reaction system. Turk J Gastroenterol. 2010 Jun;21(2):129-34.
doi: 10.4318/tjg.2010.0070. PMID: 20872325. [IF = 1.111]
86. Mishra PK*, Bhargava A, Punde RP, Pathak N, Desikan P, Jain A, Varshney S, Maudar KK. Diagnosis of gastrointestinal tuberculosis: Using cytomorphological, microbiological, immunological and molecular techniques - A study from Central India. Indian J Clin Biochem. 2010 Apr;25(2):158-63.
doi: 10.1007/s12291-010-0029-7. PMID: 23105903.
87. Nahar M, Dubey V, Mishra D, Mishra PK, Dube A, Jain NK. In vitro evaluation of surface functionalized gelatin nanoparticles for macrophage targeting in the therapy of visceral leishmaniasis. J Drug Target. 2010 Feb;18(2):93-105.
doi: 10.3109/10611860903115290. PMID: 19640212.
88. Mishra D, Mishra PK, Dabadghao S, Dubey V, Nahar M, Jain NK. Comparative evaluation of hepatitis B surface antigen-loaded elastic liposomes and ethosomes for human dendritic cell uptake and immune response. Nanomedicine (Lond). 2010 Feb;6(1):110-8.
doi: 10.1016/j.nano.2009.04.003. PMID: 19446655. [IF = 4.3]
89. Bhargava A, Punde RP, Pathak N, Dabadghao S, Desikan P, Jain A, Maudar KK, Mishra PK*. Status of inflammatory biomarkers in the population that survived the Bhopal gas tragedy: a study after two decades. Ind Health. 2010;48(2):204-8.
doi: 10.2486/indhealth.48.204. PMID: 20424351. [IF = 1.471]
90. Raghuram GV, Pathak N, Jain D, Pandey H, Panwar H, Jain SK, Banerjee S, Mishra PK*. Molecular characterization of isocyanate-induced male germ-line genomic instability. J Environ Pathol Toxicol Oncol. 2010;29(3):213-34.
doi: 10.1615/jenvironpatholtoxicoloncol.v29.i3.50. PMID: 21303328.
91. Mishra H, Mishra D, Mishra PK, Nahar M, Dubey V, Jain NK. Evaluation of solid lipid nanoparticles as carriers for delivery of hepatitis B surface antigen for vaccination using subcutaneous route. J Pharm Pharm Sci. 2010;13(4):495-509.
doi: 10.18433/j3xk53. PMID: 21486527. [IF = 1.667]
92. Mishra PK, Gulbake A, Jain A, Vyas SP, Jain SK. Targeted delivery of an anti-cancer agent via steroid coupled liposomes. Drug Deliv. 2009 Nov;16(8):437-47.
doi: 10.3109/10717540903271391. PMID: 19839788. [IF = 4.902]
93. Desikan P, De S, Mishra PK, Jain A, Panwalkar N, Verma M, Maudar KK. Comparison of performance characteristics of automated PCR systems with culture for detection of MTB complex from clinical samples in central India. Indian J Med Microbiol. 2009 Jul-Sep;27(3):277-8.
doi: 10.4103/0255-0857.53220. PMID: 19584519. [IF = 0.9]
94. Mishra PK*, Jatawa SK, Raghuram GV, Pathak N, Jain A, Tiwari A, Varshney S, Maudar KK. Correlation of aberrant expression of p53, Rad50, and cyclin-E proteins with microsatellite instability in gallbladder adenocarcinomas. Genet Mol Res. 2009 Oct 6;8(4):1202-10.
doi: 10.4238/vol8-4gmr653. PMID:19866438.
95. Mishra PK*, Raghuram GV, Panwar H, Jain D, Pandey H, Maudar KK. Mitochondrial oxidative stress elicits chromosomal instability after exposure to isocyanates in human kidney epithelial cells. Free Radic Res. 2009 Aug;43(8):718-28.
doi: 10.1080/10715760903037699. PMID: 19513903. [IF = 2.839]
96. Mishra PK*, Bhargava A, Raghuram GV, Jatawa SK, Akhtar N, Khan S, Tiwari A, Maudar KK. Induction of genomic instability in cultured human colon epithelial cells following exposure to isocyanates. Cell Biol Int. 2009 Jun;33(6):675-83.
doi: 10.1016/j.cellbi.2009.03.008. PMID: 19376255. [IF = 2.571]
97. Mishra PK*, Gorantla VR, Akhtar N, Tamrakar P, Jain SK, Maudar KK. Analysis of cellular response to isocyanate using N-succinimidyl N-methylcarbamate exposure in cultured mammalian cells. Environ Mol Mutagen. 2009 May;50(4):328-36.
doi: 10.1002/em.20469. PMID: 19197993. [IF = 3.131]
98. Mishra PK*, Dabadghao S, Modi GK, Desikan P, Jain A, Mittra I, Gupta D, Chauhan C, Jain SK, Maudar KK. In utero exposure to methyl isocyanate in the Bhopal gas disaster: evidence of persisting hyperactivation of immune system two decades later. Occup Environ Med. 2009 Apr;66(4):279.
doi: 10.1136/oem.2008.041517. PMID: 19295137. [IF = 3.824]
99. Mishra PK*, Bhargava A, Raghuram GV, Gupta S, Tiwari S, Upadhyaya R, Jain SK, Maudar KK. Inflammatory response to isocyanates and onset of genomic instability in cultured human lung fibroblasts. Genet Mol Res. 2009 Feb 10;8(1):129-43.
doi: 10.4238/vol8-1gmr544. PMID: 19283680.
100. Mishra PK*, Samarth RM, Pathak N, Jain SK, Banerjee S, Maudar KK. Bhopal Gas Tragedy: review of clinical and experimental findings after 25 years. Int J Occup Med Environ Health. 2009;22(3):193-202.
doi: 10.2478/v10001-009-0028-1. PMID: 19819837. [IF = 1.271]
101. Mishra PK*, Panwar H, Bhargava A, Gorantla VR, Jain SK, Banerjee S, Maudar KK. Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes. J Biochem Mol Toxicol. 2008 Nov-Dec;22(6):429-40.
doi: 10.1002/jbt.20260. PMID: 19111005. [IF = 3.606]
* Senior corresponding author
Patent Published :
1. I. Mittra, U. Samant, G. K. Modi, P. K. MISHRA, G. S. Bhuvaneswar
A system for ex vivo separation of apoptotic chromatin particles from blood
WIPO Patent Pub. No.: WO/2007/049286
2. I. Mittra, U. Samant, G. K. Modi, P. K. MISHRA, G. S. Bhuvaneswar
A method for ex-vivo separation of apoptotic chromatin fragments from blood or plasma for prevention and treatment of diverse human diseases
US Patent Pub. No. US20140099293A1
Books Edited :
1. Reproductive Biomedicine: From Basics to Translational Outcome, 2019, P. K. MISHRA and S. TABIBZADEH [Ed.] (ISBN:1093-9946).
2. Molecular Medicine: Bench to Bedside & Beyond, 2018, P. K. MISHRA [Associate Editor] (ISBN:978-81-936756-0-1).
3. Advances in Assisted Reproductive Technologies with Emphasis on Medical, Technical, Ethical, Legal and Social Issues, 2017, P. K. MISHRA and R. S. SHARMA [Ed.] (ISBN: 2395-2306).
4. Infertility: Causes, Mechanisms and Management, 2016, P. K. MISHRA and K. SINGH [Ed.] (ISBN:2395-2306).
5. Environmental Impacts on Reproductive Health, 2016, P. K. MISHRA and S. KUMAR [Ed.] (ISBN:2395-2306).
6. Perspectives of Reproductive Health Research on a Post - 2015 Development Framework, 2015, P. K. MISHRA and R. S. SHARMA [Ed.] (ISBN: 2395-2306).
7. Epigenetics: An Emerging Paradigm in Reproductive Health, 2014, P. K. MISHRA [Ed.] (ISBN:2395-2306).
8. Cancers of the Reproductive System: An Overview, 2012, P. K. MISHRA [Ed.] (ISBN:2395-2306).
Journals Edited (Special Issue) :
1. Reproductive biomedicine: from basics to translational outcome, Frontiers in Bioscience, USA
P. K. MISHRA, R. S. Sharma, N. K. Lohiya and S. Tabibzadeh (ed.), 2017
Monographs Published :
1. N. Pathak, P. K. MISHRA* (2020). Bioethics in Nano-Medicine: Revenons à nosmoutons ! pp 166-167(ISBN:2395-2306).
2. N. Pathak, P. K. MISHRA* (2020). Engineering Nano-Particles for Fertility Regulation: Are We There Yet? pp 92-93 (ISBN:2395-2306).
3. N. Pathak, P. K. MISHRA* (2019). Exposome - Exciting Opportunities for Research Translation in Reproductive Health, pp 119-120 (ISBN:2395-2306).
4. P. K. MISHRA*, R. S. Sharma (2019). Targeted Genome Editing by CRISPR/Cas9: Excitement and Concerns. pp 111-112 (ISBN: 2395-2306).
5. P. K. MISHRA* (2016). Environmental Impact on Reproductive Health - Can Biomarkers Offer Any Help ?, pp 7-8 (ISBN:2395-2306).
6. P. K. MISHRA* (2016). Molecular Exposomics for Assessment of Fertility Decline: An-other View, pp 58-59 (ISBN:2395-2306).
7. P. K. MISHRA* (2014). It’s Not All in Our Genes. pp 4-5 (ISBN:2395-2306).